Freier J E, Beier J C
Am J Trop Med Hyg. 1984 Jul;33(4):708-14. doi: 10.4269/ajtmh.1984.33.708.
A recently colonized strain of Aedes atropalpus was shown to be equally susceptible to oral infection with La Crosse (LAC) virus as the natural vector, Aedes triseriatus. La Crosse virus was shown to replicate and persist at high titers in orally infected Ae. atropalpus. In addition, orally infected females transmitted virus efficiently to suckling mice by mosquito bite. Transovarial transmission of LAC virus was demonstrated by recovery of virus from larval progeny after parental females were infected either orally or by intrathoracic inoculation. Virus was recovered from larval progeny that developed from eggs produced both autogenously and anautogenously. Transovarial transmission of LAC virus to F1 adults was also shown, and the filial infection rates were similar to that obtained with a strain of Ae. triseriatus used for comparison.
最近定殖的阿氏伊蚊品系被证明对拉克罗斯（LAC）病毒的口服感染与天然媒介三带喙库蚊一样易感。拉克罗斯病毒在经口感染的阿氏伊蚊中能高效复制并维持高滴度。此外，经口感染的雌蚊通过蚊虫叮咬能有效地将病毒传播给乳鼠。当亲代雌蚊经口或经胸接种感染后，从幼虫后代中分离到病毒，从而证实了拉克罗斯病毒的经卵传递。从自生和非自生产出的卵发育而来的幼虫后代中都分离到了病毒。还证明了拉克罗斯病毒能经卵传递给F1代成虫，且子代感染率与用于比较的三带喙库蚊品系相似。
