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微小棒状杆菌免疫治疗期间实体瘤患者的单核细胞功能

Monocyte function in patients with solid neoplasms during immunotherapy with Corynebacterium parvum.

作者信息

Scheinberg M A, Masuda A, Maluf J A, Mendes N F

出版信息

Cancer. 1978 May;41(5):1761-4. doi: 10.1002/1097-0142(197805)41:5<1761::aid-cncr2820410517>3.0.co;2-j.

Abstract

The present studies were performed in order to evaluate monocyte function in patients with solid neoplasms before and after administration of C. parvum. The results demonstrate that monocytes from cancer patients display increased numbers of C3 and Fc receptor sites after administration of C. parvum. It is concluded that characterization of monocyte receptor activity may be helpful in monitoring the effects of immunotherapy in the immune system.

摘要

进行本研究是为了评估实体瘤患者在给予微小隐孢子虫前后的单核细胞功能。结果表明,癌症患者的单核细胞在给予微小隐孢子虫后,C3和Fc受体位点数量增加。得出的结论是,单核细胞受体活性的特征描述可能有助于监测免疫系统中免疫治疗的效果。

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