Laplanche G, Grosshans E, Heid E, Jaeck D, Welsch M
Ann Dermatol Venereol. 1984;111(4):347-55.
A patient developed ulcerations of anus, rectum and vagina after prolonged use of suppositories containing dextropropoxyphene. Twelve identical cases have been reported in French literature. The mechanism of these ulcerations and the skin and mucosal disorders due to the principal morphinomimetic drugs opiates are briefly discussed.
一名患者在长期使用含有右丙氧芬的栓剂后出现肛门、直肠和阴道溃疡。法国文献中已报道了12例相同病例。本文简要讨论了这些溃疡的发病机制以及主要的拟吗啡类药物阿片类药物所致的皮肤和黏膜疾病。