Mustonen J
Ann Clin Res. 1984;16(3):161-6.
In a series of 184 patients with IgA glomerulonephritis (IgA GN) 114 (62%) had concomitant diseases compared with 35 (36%) in a control series consisting of 96 patients with mesangial glomerulonephritis of other type than IgA GN. This difference was statistically significant. Many of the diseases found in association with IgA GN were immunologic or systemic in nature, affected mucous membranes of the respiratory or gastrointestinal tract or were such as known to be associated with high serum IgA level. These clinical findings supported the idea that IgA GN is often a manifestation of various systemic disease processes.
在一组184例IgA肾小球肾炎(IgA GN)患者中,114例(62%)伴有其他疾病,而在另一组由96例非IgA GN型系膜增生性肾小球肾炎患者组成的对照队列中,伴有其他疾病的有35例(36%)。这一差异具有统计学意义。许多与IgA GN相关的疾病本质上属于免疫性或全身性疾病,累及呼吸道或胃肠道黏膜,或者是已知与血清IgA水平升高相关的疾病。这些临床发现支持了以下观点,即IgA GN通常是各种全身性疾病过程的一种表现。