Reikerås O
Arch Orthop Trauma Surg (1978). 1984;103(2):120-4. doi: 10.1007/BF00389584.
Changes in the mechanical properties of the rat femur caused by intramedullary application of bone cement were studied. In one group of animals reaming of the medullary cavity was performed, and bone cement was injected. In a control group only reaming was performed. At various intervals from day 0 to day 180 following operation the mechanical characteristics of the bone were evaluated. Reaming of the medullary cavity provoked a temporarily reduced bending moment of the femur at 40 days after operation. Intramedullary bone cement caused no significant changes in the bending moment of the femora until day 180 after operation. At this time, the bending moment of the cemented femora was significantly greater than that of the contralateral bones. This may be attributed to more periosteal bone being deposited, as implantation of bone cement induced a significant increase in periosteal reaction. The elastic stiffness of the bone was not altered either by reaming or the implantation of bone cement. It is concluded that reaming and implantation of bone cement into the medullary cavity do not impair the mechanical properties of the femur in the young rat.
研究了髓腔内应用骨水泥对大鼠股骨力学性能的影响。一组动物进行了髓腔扩髓并注入骨水泥，对照组仅进行扩髓。在术后第0天至第180天的不同时间间隔，评估骨骼的力学特性。髓腔扩髓在术后40天时导致股骨弯矩暂时降低。髓腔内注入骨水泥直至术后180天，股骨弯矩均无显著变化。此时，注入骨水泥的股骨弯矩显著大于对侧骨骼。这可能归因于更多骨膜骨沉积，因为骨水泥植入导致骨膜反应显著增加。扩髓或骨水泥植入均未改变骨骼的弹性刚度。结论是，在幼鼠中，髓腔扩髓和骨水泥植入不会损害股骨的力学性能。
