[不同细胞毒性作用颗粒吞噬过程中肺巨噬细胞形态功能状态的特征]
[Characteristics of the morphofunctional status of lung macrophages in the phagocytosis of particles of varying cytotoxic action].
作者信息
Kruglikov G G, Roshchenko L G, Velichkovskaia T B
出版信息
Arkh Patol. 1984;46(7):15-9.
PMID:6477169
Abstract
The cytotoxic effect of quartz and coal on phagocytizing lung macrophages was studied by transmissive and scanning electron microscopy and histochemically (the detection of acid phosphatase). The level of phagocytic activity, the activity and localization of acid phosphatase, the number and state of organelles, and the type of macrophage surface processes were shown to represent the objective criteria of the morphofunctional state of macrophages and the cytotoxic effect of the particles phagocytized.
摘要
通过透射电子显微镜、扫描电子显微镜以及组织化学方法（酸性磷酸酶检测）研究了石英和煤对肺巨噬细胞吞噬作用的细胞毒性效应。吞噬活性水平、酸性磷酸酶的活性和定位、细胞器的数量和状态以及巨噬细胞表面突起的类型均被证明是巨噬细胞形态功能状态以及吞噬颗粒细胞毒性效应的客观标准。
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