Berghaus A, Mulch G, Handrock M
Arch Otorhinolaryngol. 1984;240(2):115-23. doi: 10.1007/BF00453468.
A comparative animal study showed that, after implantation in skull defects in guinea pigs, porous high-density polyethylene (PHDPE) was substantially better anchored in the bone than Proplast, and had greater stability of form and structure. In Proplast, ingrowth of fibrous tissue caused partial structural dilatation and fragmentation, which could limit its suitability for use in reconstructive surgery.
