Ukai K, Sakakura Y, Itoh H, Miyoshi Y
Arch Otorhinolaryngol. 1984;240(2):125-32. doi: 10.1007/BF00453469.
The effect of protein malnutrition on the susceptibility of the chicken nose to Newcastle disease virus (NDV) was studied. Chicks that were rendered acutely protein-deficient for 1 or 3 weeks from the time of hatching yielded approximately 10 times more NDV from their throats than did normally fed animals 7 days after inoculation with the virus. Serum antibody responses in the protein-deficient animals 14 days after inoculation of NDV was statistically lower than in the normally fed animals. These results were supported by the mucociliary transport time in the turbinate and sinus, as well as by the histological changes in the turbinate. This difference may thus be due to the fact that normally fed maturing chicks develop an increased resistance to virus which is depressed in protein-deficient animals.
研究了蛋白质营养不良对鸡鼻对新城疫病毒（NDV）易感性的影响。从孵化时起急性蛋白质缺乏1周或3周的雏鸡，在接种病毒7天后，其喉咙中产生的新城疫病毒比正常喂食的动物多出约10倍。接种新城疫病毒14天后，蛋白质缺乏动物的血清抗体反应在统计学上低于正常喂食的动物。鼻甲和鼻窦的黏液纤毛运输时间以及鼻甲的组织学变化也支持了这些结果。因此，这种差异可能是由于正常喂食的成熟雏鸡对病毒的抵抗力增强，而蛋白质缺乏的动物则这种抵抗力下降。
