[脂质过氧化对艾氏腹水癌细胞DNA合成的影响]
[Effect of lipid peroxidation on DNA synthesis in Ehrlich ascites carcinoma cells].
作者信息
Popov G A, Konev V V
出版信息
Biokhimiia. 1984 Jul;49(7):1199-202.
PMID:6477986
Abstract
The effect of lipid peroxidation (LPO) induced by Fe2+ and linoleic acid hydroperoxides in intact cells on the rate of DNA synthesis was investigated. It was found that intensification of LPO is accompanied by a decrease of DNA synthesis rate. Under effects of linoleic acid hydroperoxides, the repression of DNA synthesis is enhanced.
摘要
研究了完整细胞中由Fe2+和亚油酸氢过氧化物诱导的脂质过氧化（LPO）对DNA合成速率的影响。发现LPO的增强伴随着DNA合成速率的降低。在亚油酸氢过氧化物的作用下，DNA合成的抑制作用增强。
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