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精神分裂症的功能性半球差异:半球间传递缺陷还是选择性半球功能障碍?

Functional hemispheric differences in schizophrenia: interhemispheric transfer deficit or selective hemisphere dysfunction?

作者信息

Hatta T, Yamamoto M, Kawabata Y

出版信息

Biol Psychiatry. 1984 Jul;19(7):1027-36.

PMID:6477988
Abstract

Two hypotheses concerning functional hemispheric organization in schizophrenic patients were examined in two experiments. In the first experiment 35 chronic schizophrenics and 35 normal controls performed tactile-visual matchings with each hand. The results showed that the performance level of the schizophrenics was inferior to that of the normal controls, but did not show any hand difference. In the second experiment chronic schizophrenics and normal controls made intermanual matchings and intramanual matchings with successively presented nonmeaningful shapes. The results revealed that the intermanual matchings of the schizophrenics were significantly inferior to those of the controls but there was no subject group difference in the intramanual matchings. These results did not lend support to the hypothesis that schizophrenics have selective left hemisphere impairment, but suggest that there may be an interhemisphere interaction deficit in schizophrenic patients.

摘要

在两项实验中检验了关于精神分裂症患者功能性半球组织的两种假说。在第一个实验中,35名慢性精神分裂症患者和35名正常对照者用每只手进行触觉-视觉匹配。结果显示,精神分裂症患者的表现水平低于正常对照者,但未表现出任何手部差异。在第二个实验中,慢性精神分裂症患者和正常对照者对相继呈现的无意义形状进行双手匹配和单手匹配。结果表明,精神分裂症患者的双手匹配明显不如对照者,但在单手匹配中没有受试者组间差异。这些结果不支持精神分裂症患者存在选择性左半球损伤的假说,但表明精神分裂症患者可能存在半球间相互作用缺陷。

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引用本文的文献

1
Interhemispheric transfer of information and schizophrenia.半球间信息传递与精神分裂症
Eur Arch Psychiatry Neurol Sci. 1990;239(5):309-13. doi: 10.1007/BF01735056.