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引用本文的文献

1
Scaling in biological nuclear magnetic resonance spectral distributions.生物核磁共振光谱分布中的标度
Biophys J. 1986 Jul;50(1):21-6. doi: 10.1016/S0006-3495(86)83435-X.

本文引用的文献

1
Carbon-13 nuclear magnetic resonance studies of cyanocobalamin and several of its analogues.钴胺素及其几种类似物的碳-13核磁共振研究。
Biochemistry. 1982 May 11;21(10):2372-8. doi: 10.1021/bi00539a015.
2
Structure of Alamethicin in solution. One- and two-dimensional 1H nuclear magnetic resonance studies at 500 MHz.溶液中短杆菌肽A的结构。在500兆赫下进行的一维和二维氢核磁共振研究。
J Mol Biol. 1983 Apr 25;165(4):757-75. doi: 10.1016/s0022-2836(83)80279-4.
3
Assignment of the 1H nuclear magnetic resonance spectrum of the trypsin inhibitor homologue K from Dendroaspis polylepis polylepis. Two-dimensional nuclear magnetic resonance at 360 and 500 MHz.多鳞树眼镜蛇胰蛋白酶抑制剂同系物K的1H核磁共振谱的归属。360和500兆赫的二维核磁共振。
J Mol Biol. 1983 Feb 5;163(4):623-46. doi: 10.1016/0022-2836(83)90115-8.
4
Tautomerism in pyridoxal phosphate and in enzymatic catalysis.
Adv Enzymol Relat Areas Mol Biol. 1979;50:1-40. doi: 10.1002/9780470122952.ch1.

生物核磁共振光谱学中的随机矩阵理论。

Random matrix theory in biological nuclear magnetic resonance spectroscopy.

作者信息

Lacelle S

出版信息

Biophys J. 1984 Aug;46(2):181-6. doi: 10.1016/S0006-3495(84)84011-4.

DOI:10.1016/S0006-3495(84)84011-4
PMID:6478032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1435036/
Abstract

The statistical theory of energy levels or random matrix theory is presented in the context of the analysis of chemical shifts of nuclear magnetic resonance (NMR) spectra of large biological systems. Distribution functions for the spacing between nearest-neighbor energy levels are discussed for uncorrelated, correlated, and random superposition of correlated energy levels. Application of this approach to the NMR spectra of a vitamin, an antibiotic, and a protein demonstrates the state of correlation of an ensemble of energy levels that characterizes each system. The detection of coherent and dissipative structures in proteins becomes feasible with this statistical spectroscopic technique.

摘要

能级统计理论或随机矩阵理论是在分析大型生物系统核磁共振（NMR）光谱化学位移的背景下提出的。讨论了最近邻能级间距的分布函数，涉及不相关、相关以及相关能级的随机叠加情况。将此方法应用于一种维生素、一种抗生素和一种蛋白质的NMR光谱，展示了表征每个系统的能级系综的相关状态。借助这种统计光谱技术，检测蛋白质中的相干结构和耗散结构变得可行。