Lantz R K, Eisenberg R B
Clin Chem. 1978 May;24(5):821-4.
A rapid extraction method preliminary to analysis for drugs in urine is described. Extraction columns containing purified cotton fiber (JETUBE, Manhattan Instrument Co., Santa Monica, Calif.) are shown to give high (approximately 90-97%) extraction efficiencies for some commonly prescribed or abused drugs, notably phenobarbital, amphetamine, morphine, and methadone. Analysis time, extraction efficiency, convenience, and eluate purity with a modified JET procedure are shown to be superior to results obtained with XAD-2 resin columns.
本文描述了一种用于尿液中药物分析的快速提取方法。结果表明,含有纯化棉纤维的提取柱(JETUBE,曼哈顿仪器公司,加利福尼亚州圣莫尼卡)对一些常用的处方药或滥用药物具有较高的提取效率(约90-97%),尤其是苯巴比妥、苯丙胺、吗啡和美沙酮。与使用XAD-2树脂柱的结果相比,改进后的JET程序在分析时间、提取效率、便利性和洗脱液纯度方面表现更优。