Ljungdahl L, Gerhardt W
Clin Chem. 1978 May;24(5):832-4.
In serum from about 800 patients, total creatine kinase and its subunit B activities were determined by the recommended Scandinavian creatine kinase method in the absence and presence of a creatine kinase M subunit inhibitory antibody. Eight patients had supranormal subunit B activities, but normal or near-normal values for total creatine kinase activity. Electrophoresis of sera from these eight patients showed, in addition to the normally migrating isoenzyme MM, one or two abnormally migrating creatine kinase isoenzyme bands, located between normally migrating isoenzymes MM and MB. Experimental data suggest that these abnormal bands may be isoenzyme BB with changed electrophoretic mobility. The eight patients had no particular disorder in common.
在约800名患者的血清中，采用推荐的斯堪的纳维亚肌酸激酶法，在不存在和存在肌酸激酶M亚基抑制抗体的情况下，测定了总肌酸激酶及其B亚基活性。8名患者的亚基B活性超常，但总肌酸激酶活性值正常或接近正常。对这8名患者的血清进行电泳分析，除了正常迁移的同工酶MM外，还出现了一条或两条异常迁移的肌酸激酶同工酶带，位于正常迁移的同工酶MM和MB之间。实验数据表明，这些异常条带可能是电泳迁移率发生改变的同工酶BB。这8名患者没有共同的特定疾病。
