Vogel E, Leskovar P, Schütz W
Eur Urol. 1984;10(4):254-9. doi: 10.1159/000463803.
Urinary organic acids were determined by gradual titration of portioned urine samples of moderately and severely recurrent stone patients and compared to those found in healthy controls. An essential deficit of organic acids was found in patients with a high recurrence rate. According to the results, the lack of organic acids in the urine of urolithiasis patients, accompanied by a reduced inhibition of the calcium-oxalate and calcium-phosphate crystallization might be causatively involved in the stone formation.
通过对中度和重度复发性结石患者的部分尿液样本进行逐步滴定来测定尿有机酸，并与健康对照者的尿有机酸进行比较。发现复发率高的患者存在必需有机酸缺乏。根据结果，尿路结石患者尿液中有机酸的缺乏，伴随着草酸钙和磷酸钙结晶抑制作用的降低，可能在结石形成中起因果作用。
