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性类固醇对虹鳟(Salmo gairdneri)嗜铬组织中儿茶酚胺生物合成的影响。

Influence of sex steroids on the catecholamine biosynthesis in chromaffin tissue from rainbow trout, Salmo gairdneri.

作者信息

Jönsson A C, Hansson T

出版信息

Gen Comp Endocrinol. 1984 Aug;55(2):200-7. doi: 10.1016/0016-6480(84)90102-3.

DOI:10.1016/0016-6480(84)90102-3
PMID:6479567
Abstract

The in vitro activities of dopamine-beta-hydroxylase (DBH) and phenylethanolamine-N-methyl transferase (PNMT) were determined in the chromaffin tissue (head kidney) of sex steroid-treated rainbow trout, Salmo gairdneri. In addition, the DBH and PNMT activities were measured in fish at different sexual states. Steroid treatment increased the wet weight of the head kidney, while both DBH and PNMT activities decreased. Although no sex difference in the enzyme activities was detected, a possible correlation between DBH and PNMT activities and increased GSI values was indicated. The presented data suggest that changes in sex steroids during development may affect the catecholamine synthesis in the chromaffin tissue in S. gairdneri.

摘要

测定了经性类固醇处理的虹鳟(Salmo gairdneri)嗜铬组织(头肾)中多巴胺-β-羟化酶(DBH)和苯乙醇胺-N-甲基转移酶(PNMT)的体外活性。此外,还测量了处于不同性状态的鱼类的DBH和PNMT活性。类固醇处理增加了头肾的湿重,而DBH和PNMT活性均降低。虽然未检测到酶活性的性别差异,但表明DBH和PNMT活性与性腺指数(GSI)值增加之间可能存在相关性。所呈现的数据表明,发育过程中性类固醇的变化可能会影响虹鳟嗜铬组织中的儿茶酚胺合成。

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