[钙拮抗剂的药理学]
[Pharmacology of calcium antagonists].
作者信息
Klaus W
出版信息
Fortschr Med. 1984 Jul 26;102(27-28):728-31.
PMID:6479816
Abstract
The present increase in indications for application of calcium antagonists--beyond the area of coronary heart disease--is confirmed by pharmacological analyses. Due to calcium antagonists the contractility is decreased, which is followed by a decreased oxygen consumption in the heart and a relaxation of the vessels. Nowadays, the anti-arrhythmic and cardio-protective effects as well as the prevention of coronary spasms by these substances can be pharmacologically established.
摘要
药理学分析证实了目前钙拮抗剂应用指征的增加——超出了冠心病领域。钙拮抗剂可降低心肌收缩力，进而降低心脏耗氧量并使血管舒张。如今，这些物质的抗心律失常和心脏保护作用以及预防冠状动脉痉挛的作用已在药理学上得到证实。
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