Kettunen P
Int J Cardiol. 1984 Sep;6(3):355-74. doi: 10.1016/0167-5273(84)90196-7.
In the present study, 78 patients with a blunt thorax trauma were examined. Fifty-four percent of the patients had been injured in traffic. Creatinine kinase (CK) and its isoenzymes (MM, MB and BB), ASAT, ALAT, ECG and thorax X-ray were taken. In 24% of the patients examined, the activity of serum MB isoenzyme was greater than or equal to 6% of the total activity of CK, and in 40% no MB activity was observed. Pathological ECG changes were detected in 89% in the MB greater than or equal to 6% group and in 32% in the MB = 0% group. ECG changes cannot be regarded as specific indicators of cardiac contusion. Arrhythmias, conduction defects, ST segment and T wave changes, and a pathologically long QTc interval were present significantly more often (P less than 0.01) in the MB greater than or equal to 6% group than in the MB = 0% group. Roentgenologically, pulmonary contusion, cardiac dilatation and venous congestion-pulmonary edema were diagnosed more frequently in the MB greater than or equal to 6% group (P less than 0.01) than in the MB = 0% group. Eleven of the patients died. A forensic autopsy was performed on these patients, and a macroscopic heart injury was detected in five of them. Serum MB activity had been found in all these five.
在本研究中,对78例钝性胸部创伤患者进行了检查。54%的患者因交通事故受伤。检测了肌酸激酶(CK)及其同工酶(MM、MB和BB)、谷草转氨酶(ASAT)、谷丙转氨酶(ALAT)、心电图(ECG)和胸部X线。在接受检查的患者中,24%的患者血清MB同工酶活性大于或等于CK总活性的6%,40%的患者未观察到MB活性。在MB大于或等于6%的组中,89%的患者检测到病理性ECG改变,在MB = 0%的组中,这一比例为32%。ECG改变不能被视为心脏挫伤的特异性指标。MB大于或等于6%的组中,心律失常、传导缺陷、ST段和T波改变以及病理性长QTc间期的出现频率明显高于(P < 0.01)MB = 0%的组。在影像学上,MB大于或等于6%的组中肺挫伤、心脏扩大和静脉淤血 - 肺水肿的诊断频率高于(P < 0.01)MB = 0%的组。11例患者死亡。对这些患者进行了法医尸检,其中5例发现有肉眼可见的心脏损伤。在所有这5例患者中均发现有血清MB活性。