Baldas J, Pojer P M
Int J Nucl Med Biol. 1984;11(2):159-62. doi: 10.1016/0047-0740(84)90053-6.
A series of dithiocarbamato complexes of 99mTc have been prepared and their potential as radiopharmaceuticals investigated in mice. The complexes ranged from non-polar and colloidal to polar and completely soluble. The non-polar complexes were rapidly extracted by the liver and then only slowly excreted while the polar complexes were cleared more slowly from the blood with concurrent rapid hepatobiliary excretion.
已制备了一系列99mTc的二硫代氨基甲酸盐配合物，并在小鼠体内研究了它们作为放射性药物的潜力。这些配合物的范围从非极性和胶体性到极性和完全可溶性。非极性配合物被肝脏迅速摄取，然后排泄缓慢，而极性配合物从血液中清除较慢，同时伴有快速的肝胆排泄。
