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新生儿手足搐搦症的镁剂治疗

Magnesium therapy in neonatal tetany.

作者信息

Turner T L, Cockburn F, Forfar J O

出版信息

Lancet. 1977 Feb 5;1(8006):283-4. doi: 10.1016/s0140-6736(77)91826-8.

DOI:10.1016/s0140-6736(77)91826-8
PMID:64807
Abstract

104 infants with symptomatic hypocalcaemia were randomly allocated to treatment with calcium gluconate, phenobarbitone, or magnesium sulphate. Infants treated with magnesium sulphate had higher plasma-calcium concentrations after 48 hours' treatment and fewer convulsions during and after the treatment period. Magnesium sulphate is recommended as the treatment of choice in symptomatic neonatal tetany whether or not there is hypomagnesaemia.

摘要

104例有症状性低钙血症的婴儿被随机分配接受葡萄糖酸钙、苯巴比妥或硫酸镁治疗。接受硫酸镁治疗的婴儿在治疗48小时后血浆钙浓度更高,且在治疗期间及之后惊厥次数更少。无论是否存在低镁血症,硫酸镁都被推荐作为有症状性新生儿手足搐搦的首选治疗方法。

相似文献

1
Magnesium therapy in neonatal tetany.新生儿手足搐搦症的镁剂治疗
Lancet. 1977 Feb 5;1(8006):283-4. doi: 10.1016/s0140-6736(77)91826-8.
2
Proceedings: Comparisons of phenobarbitone, magnesium sulphate, and calcium gluconate in treatment of neonatal hypocalcaemic convulsions.论文集:苯巴比妥、硫酸镁和葡萄糖酸钙治疗新生儿低钙惊厥的比较
Arch Dis Child. 1974 Mar;49(3):244. doi: 10.1136/adc.49.3.244.
3
[Effective treatment of tetany in a newborn infant by combined administration of magnesium and calcium].[联合使用镁和钙有效治疗新生儿手足搐搦症]
Nihon Shonika Gakkai Zasshi. 1971 Oct;75(10):913-6.
4
Association of oedema and hypomagnesaemia with hypocalcaemic tetany of the newborn.新生儿水肿、低镁血症与低钙血症性手足搐搦的关联。
Br Med J. 1971 Jul 3;3(5765):15-8. doi: 10.1136/bmj.3.5765.15.
5
Parathormone-like effect of magnesium replenishment in steatorrhea.补充镁对脂肪泻的类甲状旁腺激素样作用。
N Engl J Med. 1970 Jan 8;282(2):61-8. doi: 10.1056/NEJM197001082820203.
6
[Studies on serum Mg and Ca levels in cattle with grass tetany on hypocalcemia before and following infusion with high Mg and medium or high Ca concentrations].[关于低血钙性牧草痉挛牛在输注高镁及中或高钙浓度前后血清镁和钙水平的研究]
Arch Exp Veterinarmed. 1976;30(4):567-84.
7
Prevention of early neonatal hypocalcemia in low birth weight infants with continuous calcium infusion: effect on serum calcium, phosphorus, magnesium, and circulating immunoreactive parathyroid hormone and calcitonin.持续输注钙剂预防低出生体重儿早期新生儿低钙血症:对血清钙、磷、镁以及循环免疫反应性甲状旁腺激素和降钙素的影响
Pediatr Res. 1977 Dec;11(12):1180-5. doi: 10.1203/00006450-197712000-00003.
8
[Parenteral administration of magnesium in spasmophilia].[痉挛性疾病中镁的胃肠外给药]
Rev Med Brux. 1986 Mar;7(3):145-8.
9
Letter: Neonatal seizures and calcium.
N Engl J Med. 1973 Dec 6;289(23):1253. doi: 10.1056/nejm197312062892317.
10
[Therapy of the tetany syndrome].[手足搐搦综合征的治疗]
Dtsch Med Wochenschr. 1985 Mar 15;110(11):424-7. doi: 10.1055/s-2008-1068840.

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Nat Genet. 2014 Dec;46(12):1274-82. doi: 10.1038/ng.3129. Epub 2014 Oct 26.
2
Magnesium (and trace substance) deficiencies in the pathogenesis of cancer.癌症发病机制中的镁(和痕量物质)缺乏。
Biol Trace Elem Res. 1979 Dec;1(4):273-97. doi: 10.1007/BF02778831.
3
Serum magnesium level and sleep behavior of newborn infants.
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