Turner T L, Cockburn F, Forfar J O
Lancet. 1977 Feb 5;1(8006):283-4. doi: 10.1016/s0140-6736(77)91826-8.
104 infants with symptomatic hypocalcaemia were randomly allocated to treatment with calcium gluconate, phenobarbitone, or magnesium sulphate. Infants treated with magnesium sulphate had higher plasma-calcium concentrations after 48 hours' treatment and fewer convulsions during and after the treatment period. Magnesium sulphate is recommended as the treatment of choice in symptomatic neonatal tetany whether or not there is hypomagnesaemia.
104例有症状性低钙血症的婴儿被随机分配接受葡萄糖酸钙、苯巴比妥或硫酸镁治疗。接受硫酸镁治疗的婴儿在治疗48小时后血浆钙浓度更高,且在治疗期间及之后惊厥次数更少。无论是否存在低镁血症,硫酸镁都被推荐作为有症状性新生儿手足搐搦的首选治疗方法。