Hunter M G
J Endocrinol. 1984 Oct;103(1):107-10. doi: 10.1677/joe.0.1030107.
Human luteal tissue recovered from varying stages of the luteal phase was minced and incubated for 3 h and the effect of human chorionic gonadotrophin (hCG), prolactin and hCG + prolactin on progesterone and oestradiol production measured. While hCG generally enhanced both progesterone and oestradiol synthesis, prolactin alone at either 20 or 200 micrograms/l had no significant effect on steroidogenesis. When prolactin was added along with hCG in four of six corpora lutea, however, progesterone production significantly increased and in three of six corpora lutea oestradiol production was increased above that induced by hCG alone. It is concluded that prolactin may play some role in the control of steroidogenesis by the human corpus luteum.
从黄体期不同阶段获取的人黄体组织被切碎并孵育3小时，检测人绒毛膜促性腺激素（hCG）、催乳素以及hCG + 催乳素对孕酮和雌二醇生成的影响。虽然hCG通常会增强孕酮和雌二醇的合成，但单独使用20或200微克/升的催乳素对类固醇生成没有显著影响。然而，在六个黄体中的四个中，当催乳素与hCG一起添加时，孕酮生成显著增加，并且在六个黄体中的三个中，雌二醇生成增加至高于单独hCG诱导的水平。得出的结论是，催乳素可能在人黄体对类固醇生成的控制中发挥一定作用。
