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灰黄霉素在头癣中的间歇使用。

Intermittent use of griseofulvin in tinea capitis.

作者信息

Oskui J

出版信息

Cutis. 1978 May;21(5):689-92.

PMID:648169
Abstract

A total of 247 patients with tinea capitis were divided into two groups and treated with griseofulvin in two different ways: the first group received the drug every other day, and the second received it twice a week. The dosage was 5 mg/lb, with a maximum of 1 gm/day in both cases. In the first group, 99 percent of the patients were completely cured within seven weeks. Of those who received the griseofulvin twice a week, 91 percent were completely cleared within eight weeks. None of those in either group showed any signs of side effects from the medication.

摘要

共有247名头癣患者被分为两组,采用两种不同方式使用灰黄霉素进行治疗:第一组每隔一天用药一次,第二组每周用药两次。剂量均为5毫克/磅,两组每日最大剂量均为1克。第一组中,99%的患者在七周内完全治愈。在每周接受两次灰黄霉素治疗的患者中,91%在八周内完全康复。两组患者均未出现该药物的任何副作用迹象。

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