Tyrer L B
J Reprod Med. 1984 Jul;29(7 Suppl):551-9.
Sexual activity among unmarried women aged 15-19 living in metropolitan areas rose 66% in the 1970s. Additionally, teenage pregnancies average 1.2 million yearly. However, based largely upon a 25% increase in contraceptive use, the pregnancy rate among teenagers declined 15% between 1973 and 1978. The data on the use of various contraceptive methods by women aged 15-19 show the Pill to be the first choice (1,539,000). Oral contraceptives are safest for young women, with rare risks of serious cardiovascular complications and no deaths reported from cardiovascular disease for women under 18. In contrast, the mortality risk associated with childbirth for this age group is 11.1 deaths per 100,000 live births. Noncontraceptive health benefits associated with oral contraceptive use, such as a 50% decrease in the risk of developing pelvic inflammatory disease, resulting in a protective effect on future fertility, is an excellent rationale for prescribing the Pill for young women who are sexually active. The pill of choice should be one with low doses of both estrogen and progestin yet doses high enough to minimize break-through bleeding, for such bleeding is the most frequent cause of discontinuation. Adolescents require careful screening for contraindications to Pill use prior to initial prescription plus frequent follow-up and monitoring so as to minimize side effects and maximize compliance and continuation of use.
20世纪70年代,居住在大都市地区的15至19岁未婚女性的性活动增加了66%。此外,青少年每年平均怀孕120万例。然而,由于避孕药具的使用增加了25%,1973年至1978年间青少年的怀孕率下降了15%。15至19岁女性使用各种避孕方法的数据显示,避孕药是首选(153.9万例)。口服避孕药对年轻女性最安全,严重心血管并发症的风险罕见,18岁以下女性没有因心血管疾病死亡的报告。相比之下,这个年龄组与分娩相关的死亡风险为每10万例活产11.1例死亡。口服避孕药使用带来的非避孕健康益处,如盆腔炎发病风险降低50%,对未来生育产生保护作用,这是为性活跃的年轻女性开避孕药的一个很好的理由。选择的避孕药应该是雌激素和孕激素剂量都低但又足够高以尽量减少突破性出血的那种,因为这种出血是停药最常见的原因。青少年在首次开处方前需要仔细筛查避孕药使用的禁忌症,并进行频繁的随访和监测,以尽量减少副作用,最大限度地提高依从性和持续使用率。