Uchida K, Shimazui T, Nemoto R, Kano S, Koiso K
Jpn J Clin Oncol. 1984 Sep;14(3):369-77.
The clinical aspects of 64 patients with superficial bladder cancer (Ta, T1, T2 according to the TNM classification, International Union against Cancer or Stage O, A, B1 according to Marshall) admitted to the Tsukuba University Hospital were analyzed retrospectively. Treatment of these patients was mainly by transurethral surgery. The overall 10-year survival rate was 73%. Eight patients died and four of them showed an invasive change, the so-called metamorphosis, during the follow-up period. Patients with papillary, pedunculated tumors had better survival rates than those with papillary, sessile tumors. Patients with tumors less than 1 cm in size had better survival rates than those with tumors 1-3 cm in size. There were no statistical differences in survival rates between patients with single and multiple tumors. Up to seven years from surgery, the patients with T2 tumors had lower survival rates than those with Ta-T1 tumors. The patients with grade I tumors had better survival rates than those with grade II tumors. There were no significant differences in recurrence rates related to the grade of the tumor. It is thought that the prognosis of superficial bladder cancer in our series depended mainly on the shape, size, number, depth and grade of the tumor.
对筑波大学医院收治的64例浅表性膀胱癌患者（根据国际抗癌联盟TNM分类为Ta、T1、T2期，或根据马歇尔分类为O期、A期、B1期）的临床情况进行了回顾性分析。这些患者的治疗主要采用经尿道手术。总体10年生存率为73%。8例患者死亡，其中4例在随访期间出现侵袭性改变，即所谓的蜕变。有蒂乳头状肿瘤患者的生存率高于无蒂乳头状肿瘤患者。肿瘤大小小于1 cm的患者生存率高于肿瘤大小为1 - 3 cm的患者。单发和多发肿瘤患者的生存率无统计学差异。术后长达7年，T2期肿瘤患者的生存率低于Ta - T1期肿瘤患者。I级肿瘤患者的生存率高于II级肿瘤患者。肿瘤分级与复发率无显著差异。据认为，本系列浅表性膀胱癌的预后主要取决于肿瘤的形态、大小、数量、深度和分级。
