Zharinov G M
Med Radiol (Mosk). 1984 Sep;29(9):59-62.
The results of therapy of 949 patients with cervical cancer are analysed. Therapy was provided in the form of a concomitant method, 60Co agents with low activity were used in intracavitary irradiation. It has been established that doses of 50-70 Gy ensure high 5-year survival rates of patients with Stage I cervical cancer. In patients with Stage II and Stage III cervical cancer survival rates were the highest within the range of 50-70 Gy. A further increase in the absorbed dose level deteriorated the survival rates of the patients, the frequency of local tumor control was not elevated. It is recommended that optimum dose levels be adhered to even during treatment of patients with disseminated cervical cancer.
分析了949例宫颈癌患者的治疗结果。治疗采用同步放化疗方法，腔内照射使用低活度60Co放射源。已证实，50 - 70 Gy的剂量可确保I期宫颈癌患者的5年生存率较高。II期和III期宫颈癌患者在50 - 70 Gy范围内生存率最高。吸收剂量水平的进一步增加会使患者生存率恶化，局部肿瘤控制率并未提高。建议即使在治疗播散性宫颈癌患者时也应坚持最佳剂量水平。
