Morini A, Pelliccia G, Mauceri P, Grandi M
Minerva Med. 1984 Aug 25;75(32-33):1893-8.
Starting from the consideration that communications relating to antidepressant drugs are chiefly reported by psychiatrists and that such reports deal with cases that we don't find in general practice, or at least marginally, the authors go on considering again their material consisting of 944 patients treated with antidepressants alone or associated with tranquilizers and/or with neuroplegic sedatives, hoping to gather usefull informations for a better definition of the role of these drugs in this large nosographic area. The authors could, therefore, by that way: confirm the high incidence of psychosomatic disorders among all the professional areas concerned with general practice; confirm the clear prevalence of the less symptomatic forms; verify in a high percentage of cases the coexistence of an organic disorder in way of progress or in outcome; confirm the double role of these drugs, diagnostic (ex-juvantibus) and therapeutical; suggest a third role of nosographic nature.
考虑到有关抗抑郁药物的报告主要由精神科医生提供,且这些报告涉及的病例在一般临床实践中并不常见,或者至少只是少数情况,作者们再次审视了他们收集的944例仅使用抗抑郁药物治疗,或联合使用镇静剂和/或神经安定镇静剂治疗的患者资料,希望能收集到有用信息,以便更好地界定这些药物在这一广泛疾病分类领域中的作用。因此,作者们通过这种方式可以:证实在所有涉及一般临床实践的专业领域中心身疾病的高发病率;证明显症状较轻的形式明显占优势;在高比例的病例中证实存在进行性或转归期的器质性疾病;证实这些药物的双重作用,即诊断性(辅助性)和治疗性;提出疾病分类性质的第三种作用。