Sahgal A, Wright C
Neurosci Lett. 1984 Aug 10;48(3):299-304. doi: 10.1016/0304-3940(84)90054-5.
Latency measures from passive avoidance studies are frequently used as an index of memory. Thus, vasopressin (VP) is thought to enhance memory, since it has been shown to increase re-entry latencies. Conversely, several substances, such as oxytocin (OT), are supposed to have amnestic effects since they may decrease latencies. We describe a novel avoidance design, which allows latency to be assessed, but also permits the animal to re-enter into a distinctive compartment where shock had not been experienced (choice measure). Latency scores indicated that VP may improve memory, but the choice index suggested that this was not the case.
来自被动回避研究的潜伏期测量常常被用作记忆指标。因此，血管加压素（VP）被认为可增强记忆，因为已证明它能增加再次进入潜伏期。相反，几种物质，如催产素（OT），被认为具有遗忘作用，因为它们可能会缩短潜伏期。我们描述了一种新颖的回避设计，它既能评估潜伏期，又能让动物再次进入一个未经历电击的独特隔室（选择测量）。潜伏期分数表明VP可能改善记忆，但选择指数表明情况并非如此。
