Mumenthaler M, Treig T
Schweiz Med Wochenschr. 1984 Aug 25;114(34):1163-70.
A typical episode of transient global amnesia has been observed in 111 personal cases. In these elderly patients a sudden disturbance of memory, which may last several hours, makes it impossible for them to store fresh information. During this period there is also retrograde amnesia which covers a period of several weeks or months prior to onset of the acute episode. The disturbance ends suddenly and the retrograde amnesia gap fills up again. The age distribution, vascular risk factors and triggering mechanisms in these personal cases are described. 22 of 111 patients had 1 or more relapses, in one case after a 15 years' interval. It is our opinion that transient global amnesia is a vascular disturbance in the hippocampal region. One example of localized (ischemic) area in this region has been shown by computed tomography.
在111例个人病例中观察到典型的短暂性全面性遗忘发作。在这些老年患者中,记忆力突然受到干扰,可能持续数小时,导致他们无法存储新信息。在此期间,也存在逆行性遗忘,涵盖急性发作前几周或几个月的时间段。这种干扰突然结束,逆行性遗忘的间隙又再次填满。描述了这些个人病例中的年龄分布、血管危险因素和触发机制。111例患者中有22例复发1次或多次,其中1例间隔15年后复发。我们认为短暂性全面性遗忘是海马区的血管性障碍。计算机断层扫描已显示该区域局部(缺血)区域的一个实例。