Izembart M, Richardot G, de Crémoux P, Digioia Y, Vallée G
Schweiz Med Wochenschr. 1984 Sep 8;114(36):1227-32.
Investigations in 6 cases of congenital or acquired athyreosis show that serum thyroglobulin determined in these cases by radioimmunology is not due to a determination artifact or to another protein, but that, with regard to immunoreactivity, molar mass and isoelectric point, it displays all the features of the standard thyroglobulin of thyroid origin and of the serum thyroglobulin of normal subjects. The authors conclude that small quantities of thyroglobulin are present in the serum of such patients, even where all the other criteria of athyrosis appear to be present.
对6例先天性或后天性甲状腺缺失患者的研究表明,通过放射免疫法测定的这些患者血清甲状腺球蛋白并非测定假象或其他蛋白质所致,而是在免疫反应性、摩尔质量和等电点方面,它表现出甲状腺来源的标准甲状腺球蛋白以及正常受试者血清甲状腺球蛋白的所有特征。作者得出结论,即使在所有其他甲状腺缺失标准似乎都存在的情况下,此类患者血清中仍存在少量甲状腺球蛋白。