Khayyal M T, Mousa A H, Saleh S, Abo-HASHISH M A, Metwally A A
Egypt J Bilharz. 1978;4(1):89-96.
THE LIPID pattern of blood and liver of mice infected with S. mansoni as well as in male and female worms was studied. Experiments were also carried out on non-infected and infected mice after treatment with Niridazole. It was found that Niridazole caused a significant increase in liver triglycerides and serum free acids. These changes were more pronounced in non-infected animals than in infected ones. The drug was found to reduce worm phospholipids and to increase their triglyceride level. The male worms were more affected than the female ones.
研究了感染曼氏血吸虫的小鼠血液和肝脏以及雄虫和雌虫的脂质模式。还对未感染和感染硝唑咪后的小鼠进行了实验。发现硝唑咪导致肝脏甘油三酯和血清游离酸显著增加。这些变化在未感染动物中比在感染动物中更明显。发现该药物可降低虫体磷脂并增加其甘油三酯水平。雄虫比雌虫受影响更大。
