Kusakari J, Inamura N, Sakurai T, Kawamoto K
Tohoku J Exp Med. 1984 Jul;143(3):351-9. doi: 10.1620/tjem.143.351.
The effects of hypothermia upon electrocochleogram (ECochG) and auditory evoked brainstem response (ABR) were studied in 10 children who underwent the open heart surgery under hypothermic anesthesia. The latencies of N1, waves III and V in response to click of 115 dB p.e. SPL were prolonged at the rate of 0.12 +/- 0.02, 0.25 +/- 0.04 and 0.43 +/- 0.05 msec/degree C, respectively. The N1 amplitude was initially increased, returned to the precooling value at about 26 degrees C and decreased thereafter. SP was increased in amplitude by hypothermia and never disappeared throughout the observation. At the time of rewarming, SP appeared first, followed by N1 and finally by waves III and V. The results obtained in the present study were discussed in the light of the sensitivity of the sensory hair cells, peripheral nerves and CNS to the hypothermic condition.
在10名接受低温麻醉下心脏直视手术的儿童中，研究了低温对耳蜗电图（ECochG）和听觉诱发电位脑干反应（ABR）的影响。对115 dB声压级峰值等效连续声压级（p.e. SPL）的短声刺激，N1波、III波和V波的潜伏期分别以0.12±0.02、0.25±0.04和0.43±0.05毫秒/摄氏度的速率延长。N1波振幅最初增加，在约26摄氏度时恢复到预冷值，此后下降。SP的振幅因低温而增加，在整个观察过程中从未消失。复温时，SP最先出现，其次是N1波，最后是III波和V波。根据感觉毛细胞、周围神经和中枢神经系统对低温状态的敏感性，对本研究获得的结果进行了讨论。
