Kozma D, Mihalik P
Z Erkr Atmungsorgane. 1984;162(3):249-55.
Case report on a 40 years old patient with pulmonary tuberculosis, in whom a treatment with Rifampicin plus Ethambutol has caused a transient hepatic and renal failure. By histology a chronic aggressive hepatitis and a destruction of renal tubular epithelium could be found. The etiologic role of Rifampicin is believed to be probable. Pathomechanism and differential diagnosis are discussed.
一名40岁肺结核患者的病例报告,该患者接受利福平加乙胺丁醇治疗后出现短暂性肝肾功能衰竭。通过组织学检查发现慢性侵袭性肝炎和肾小管上皮破坏。利福平的病因学作用被认为很可能存在。文中讨论了发病机制和鉴别诊断。