Bittner H, Gläser A
Z Exp Chir Transplant Kunstliche Organe. 1984;17(4):230-5.
The application of methotrexate led in Wistar rats to the known toxic effects. Malignant human melanoma cells can be transplanted in pretreated animals by contribution of the immunosuppression by means of Azathioprine. The transplanted tumors spread and proliferate in the organism of the receiver.
在Wistar大鼠中应用甲氨蝶呤会导致已知的毒性作用。通过硫唑嘌呤进行免疫抑制，可将人类恶性黑色素瘤细胞移植到预处理过的动物体内。移植的肿瘤会在受体动物体内扩散和增殖。
