Heublein B, Rössler U, Schulte R, Bartel J
Z Kardiol. 1984 Jul;73(7):466-71.
Actual possibilities and limitations in fetal echocardiography (two-dimensional and impulse-Doppler technique) based on our own experiences in 53 cases are described. Morphological analysis was almost successful after the 22nd week of gestation, in 11.3% the imaging was inadequate as the result of unfavorable ultrasound viewing. In twins especially the morphological analysis of the second fetus was more difficult. Clear morphological differentiation from the important parts of the fetus heart was possible after the 30th week of gestation in the majority of cases. From 47 sonographically judgeable fetal hearts 3 were classified as malformations. One of them could be confirmed by autopsy (ventricle-septal defect combined with cor monatrium), the second case clinically/echocardiographically postpartally respectively (atrial septal defect - secundum type). On the other hand the third pathological diagnosis of fetal echocardiography (single ventricle) could not be confirmed post-natally. As the result of this preliminary study fetal echocardiography can currently provide some important clues for the selection, perinatological treatment and care in birth of the child with a potentially higher risk factor. Additionally the authors point out the possibilities of complex functional analysis of the fetal heart under different pharmacological treatment.
基于我们自身53例病例的经验，描述了胎儿超声心动图（二维和脉冲多普勒技术）的实际可能性和局限性。妊娠22周后形态学分析几乎都能成功，11.3%的病例因超声观察条件不佳导致成像不充分。尤其是双胞胎，对第二个胎儿的形态学分析更困难。大多数情况下，妊娠30周后可以清晰地从胎儿心脏的重要部位进行形态学区分。在47个超声可判断的胎儿心脏中，3个被归类为畸形。其中一个通过尸检得以证实（室间隔缺损合并共同心房），第二例分别在产后通过临床/超声心动图得到证实（继发孔型房间隔缺损）。另一方面，胎儿超声心动图的第三个病理诊断（单心室）产后未得到证实。这项初步研究的结果表明，目前胎儿超声心动图可为筛选、围产期治疗以及对有潜在高风险因素的儿童出生护理提供一些重要线索。此外，作者指出了在不同药物治疗下对胎儿心脏进行复杂功能分析的可能性。
