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[一价铊盐对大鼠肝脏线粒体的作用]

[Action of the salts of univalent thallium on the liver mitochondria of the rat].

作者信息

Skul'skiĭ I A, Ivanova T I, Savina M V

出版信息

Zh Evol Biokhim Fiziol. 1984 Jul-Aug;20(4):353-5.

PMID:6485653
Abstract

Using light scattering and electron microscopic techniques, studies have been made of the swelling of liver mitochondria in isotonic sucrose solutions containing different concentrations of nitrate or acetate of monovalent thallium. It was concluded that the injurious effect of thallium on the mitochondria is associated with both its penetration into intramitochondrial space, and interaction of the external thallium with mitochondrial membranes.

摘要

利用光散射和电子显微镜技术,对肝线粒体在含有不同浓度一价铊的硝酸盐或醋酸盐的等渗蔗糖溶液中的肿胀情况进行了研究。得出的结论是,铊对线粒体的损伤作用既与其穿透线粒体内空间有关,也与外部铊与线粒体膜的相互作用有关。

相似文献

1
[Action of the salts of univalent thallium on the liver mitochondria of the rat].[一价铊盐对大鼠肝脏线粒体的作用]
Zh Evol Biokhim Fiziol. 1984 Jul-Aug;20(4):353-5.
2
Inorganic phosphate stimulates the toxic effects of Tl+ in rat liver mitochondria.无机磷酸盐会刺激铊离子(Tl+)对大鼠肝脏线粒体产生毒性作用。
J Biochem Mol Toxicol. 2008 May-Jun;22(3):148-57. doi: 10.1002/jbt.20215.
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[Reversible changes in the volume of isolated mitochondria in the course of ion flux oscillations between the mitochondria and the medium].[线粒体与介质之间离子通量振荡过程中分离线粒体体积的可逆变化]
Tsitologiia. 1982 Sep;24(9):1024-7.
4
Effects of Tl(+) on ion permeability, membrane potential and respiration of isolated rat liver mitochondria.铊离子(Tl⁺)对离体大鼠肝线粒体离子通透性、膜电位及呼吸作用的影响。
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Salicylate and mitochondrial injury in Reye's syndrome.瑞氏综合征中的水杨酸盐与线粒体损伤。
Science. 1983 Jul 8;221(4606):163-5. doi: 10.1126/science.6857275.
6
Tl+ increases the permeability of the inner membranes of rat liver mitochondria for monovalent cations.
Dokl Biochem Biophys. 2001 May-Jun;378:145-9. doi: 10.1023/a:1011538906694.
7
[Effect of cadmium ions on the respiration, cation transport and morphology of the liver mitochondria in the rat and the lamprey].[镉离子对大鼠和七鳃鳗肝脏线粒体呼吸、阳离子转运及形态的影响]
Tsitologiia. 1988 Aug;30(8):956-62.
8
Uptake of thallous ions by mitochondria is stimulated by nonactin but not by respiration alone.线粒体对铊离子的摄取受到缬氨霉素的刺激,但仅靠呼吸作用则不会。
Eur J Biochem. 1981 Nov;120(2):263-6. doi: 10.1111/j.1432-1033.1981.tb05698.x.
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[The effect of Cd2+ on the respiration and swelling of isolated rat liver mitochondria in incubation media of different compositions].[不同成分孵育介质中镉离子对离体大鼠肝线粒体呼吸及肿胀的影响]
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Dextran causes aggregation of mitochondria and influences their oxidoreductase activities and light scattering.右旋糖酐会导致线粒体聚集,并影响其氧化还原酶活性和光散射。
Arch Biochem Biophys. 2003 Apr 15;412(2):176-85. doi: 10.1016/s0003-9861(03)00034-1.

引用本文的文献

1
Influence of Tl(+) on mitochondrial permeability transition pore in Ca(2+)-loaded rat liver mitochondria.Tl(+)对 Ca(2+)负载的大鼠肝线粒体中线粒体通透性转换孔的影响。
J Bioenerg Biomembr. 2011 Apr;43(2):149-62. doi: 10.1007/s10863-011-9341-z. Epub 2011 Mar 19.
2
Effects of Tl(+) on ion permeability, membrane potential and respiration of isolated rat liver mitochondria.铊离子(Tl⁺)对离体大鼠肝线粒体离子通透性、膜电位及呼吸作用的影响。
J Bioenerg Biomembr. 2009 Jun;41(3):277-87. doi: 10.1007/s10863-009-9225-7. Epub 2009 Jul 22.