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淋巴细胞去除术治疗多发性硬化症:一项初步研究

Lymphocytapheresis therapy in multiple sclerosis, a preliminary study.

作者信息

Medaer R, Eeckhout C, Gautama K, Vermijlen C

出版信息

Acta Neurol Scand. 1984 Aug;70(2):111-5. doi: 10.1111/j.1600-0404.1984.tb00811.x.

Abstract

10 patients with definite multiple sclerosis (MS), most of them with the chronic progressive type, were treated with lymphocytapheresis during one year. The DSS (Disability Status Scale) improved in 4 patients during the intensive phase of treatment, remained stable in 5 patients and deteriorated in one. The NSS (Neurological Status Scale) showed a stabilisation for the majority of the neurologic functions. Using the ISS (Incapacity Status Scale), an improvement was measured in 6 patients, a stabilisation in one and a deterioration in 3. Exacerbations could not be prevented by lymphocytapheresis.

摘要

10例确诊为多发性硬化症(MS)的患者,其中大多数为慢性进行性类型,在一年时间内接受了淋巴细胞去除术治疗。在治疗强化阶段,4例患者的残疾状态量表(DSS)有所改善,5例患者保持稳定,1例患者病情恶化。神经状态量表(NSS)显示大多数神经功能保持稳定。使用失能状态量表(ISS)测量,6例患者有所改善,1例稳定,3例恶化。淋巴细胞去除术无法预防病情加重。

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Lymphocytoplasmapheresis in multiple sclerosis: one-year results in 6 patients.
Ital J Neurol Sci. 1986 Feb;7(1):119-23. doi: 10.1007/BF02230429.

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