Høvding G
Acta Ophthalmol (Copenh). 1984 Aug;62(4):566-76. doi: 10.1111/j.1755-3768.1984.tb03969.x.
Hydrophilic 'bandage' lenses were fitted in 107 patients with corneal disorders not satisfactorily responding to conventional medical treatment. An over-all beneficial effect on both ocular discomfort, visual acuity and corneal disorder was found (P less than 0.002). Regarding each group separately only patients with bullous keratopathy and those with corneal ulcers achieved a significant reduction of ocular discomfort (P less than 0.002) and a significant improvement of visual acuity (P less than 0.05 - P less than 0.01). In bullous keratopathy corneal oedema was significantly reduced by concomitant use of contact lenses and 5% NaCl eye drops (P less than 0.01). Significant improvement of corneal disorder occurred in patients with corneal ulcers and in those with corneal lacerations (P less than 0.002 and P less than 0.01, respectively). Complications included corneal vascularization (7.5%) and keratitis/keratoconjunctivitis (5.6%). Prophylactic use of topical antibiotics appeared necessary only in dry eye disease.
对107例采用传统药物治疗效果不佳的角膜疾病患者佩戴亲水性“绷带”镜片。结果发现,该镜片对眼部不适、视力及角膜疾病均有显著的总体改善效果(P<0.002)。单独来看,仅大泡性角膜病变患者和角膜溃疡患者的眼部不适有显著减轻(P<0.002),视力有显著提高(P<0.05 - P<0.01)。在大泡性角膜病变中,同时使用隐形眼镜和5%氯化钠滴眼液可显著减轻角膜水肿(P<0.01)。角膜溃疡患者和角膜裂伤患者的角膜疾病有显著改善(分别为P<0.002和P<0.01)。并发症包括角膜血管化(7.5%)和角膜炎/角膜结膜炎(5.6%)。仅在干眼症中预防性使用局部抗生素似乎是必要的。