Hägnevik K, Faxelius G, Irestedt L, Lagercrantz H, Lundell B, Persson B
Acta Paediatr Scand. 1984 Sep;73(5):602-9. doi: 10.1111/j.1651-2227.1984.tb09982.x.
The immediate postnatal metabolic adaptation and sympatho-adrenal activation were studied in infants delivered vaginally or by elective caesarean section. Vaginally delivered infants showed high catecholamine levels at birth compared to infants born by caesarean section under epidural or general anaesthesia. Umbilical arterial glucose levels were significantly higher in the vaginal group than in both caesarean section groups. At 30 min, all groups showed a marked decrease with several infants showing asymptomatic hypoglycaemia in the caesarean section group. C-peptide levels showed no difference at birth but later became significantly higher in the vaginal group. Although the levels of free fatty acids and glycerol were low at birth, they were significantly higher in the vaginal group. In all groups they increased substantially with time. Considering the marked differences in catecholamine levels, the differences in metabolic adaptation were unexpectedly small. This implies an attenuated metabolic response to sympatho-adrenal stimulation in the newborn.
对经阴道分娩或择期剖宫产的婴儿进行了出生后即刻的代谢适应和交感-肾上腺激活情况研究。与在硬膜外麻醉或全身麻醉下剖宫产出生的婴儿相比，经阴道分娩的婴儿出生时儿茶酚胺水平较高。阴道分娩组脐动脉血糖水平显著高于两个剖宫产组。30分钟时，所有组均出现显著下降，剖宫产组有几名婴儿出现无症状低血糖。出生时C肽水平无差异，但随后阴道分娩组显著升高。尽管出生时游离脂肪酸和甘油水平较低，但阴道分娩组显著更高。所有组中它们均随时间大幅增加。考虑到儿茶酚胺水平存在显著差异，代谢适应方面的差异出人意料地小。这意味着新生儿对交感-肾上腺刺激的代谢反应减弱。
