Ivanova L N, Archibasova V K, Shterental' I Sh
Fiziol Zh SSSR Im I M Sechenova. 1978 Mar;64(3):358-63.
The sodium deposing function of the skin in Wistar albino rats under conditions of different salt loads were studied. 6 mEq NaCl per os was followed by an increase in sodium content of the skin on account of the exchangeable fraction. The diet with high content of sodium (15 mEq a day during 30 days) led to saturation of the skin storage structures, the blood sodium concentration after a single salt load increasing sharply. The storage of sodium in the skin is, evidently, carried out with the aid of the cation by glycosamino--glycans. The increase in exchangeable sodium of the skin under the condition of highsodium regimen is, evidently, due to an increase in sulphated GAG.
研究了不同盐负荷条件下Wistar白化大鼠皮肤的排钠功能。经口给予6 mEq氯化钠后,由于可交换部分,皮肤中的钠含量增加。高钠饮食(30天内每天15 mEq)导致皮肤储存结构饱和,单次盐负荷后血钠浓度急剧升高。皮肤中钠的储存显然是借助阳离子通过糖胺聚糖进行的。高钠方案条件下皮肤可交换钠的增加显然是由于硫酸化糖胺聚糖的增加。