颈动脉内膜切除术期间使用巴比妥类药物进行脑保护的经验。
Experience with barbiturate therapy for cerebral protection during carotid endarterectomy.
作者信息
McMeniman W J, Fletcher J P, Little J M
出版信息
Ann R Coll Surg Engl. 1984 Sep;66(5):361-4.
Abstract
Carotid endarterectomy was performed 28 times in 27 patients. All but one patient had symptomatic carotid artery disease, 59% had bilateral disease and 59% had associated intracranial disease. Barbiturate therapy was used as a means of cerebral protection during carotid artery cross-clamping. Neurological deficit occurred in two patients, being permanent in one patient (3.5%); both patients had bilateral carotid and intracranial disease and both had carotid stump pressures greater than 55 mmHg. No morbidity could be attributed to barbiturate usage.
摘要
27例患者共接受了28次颈动脉内膜切除术。除1例患者外，其余均患有症状性颈动脉疾病，59%为双侧疾病，59%伴有颅内疾病。巴比妥类药物疗法被用作颈动脉交叉钳夹期间的脑保护手段。2例患者出现神经功能缺损，其中1例为永久性缺损（3.5%）；这2例患者均患有双侧颈动脉和颅内疾病，且颈动脉残端压力均大于55 mmHg。未发现巴比妥类药物使用导致的并发症。
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A pilot protocol and review of triple neuroprotection with targeted hypothermia, controlled induced hypertension, and barbiturate infusion during emergency carotid endarterectomy for acute stroke after failed tPA or beyond 24-hour window of opportunity.一项关于在tPA治疗失败或超过24小时机会窗的急性卒中患者进行紧急颈动脉内膜切除术期间，采用靶向低温、控制性诱导高血压和巴比妥酸盐输注进行三重神经保护的初步方案及综述。
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