α-酮酸与L-刀豆氨酸之间的肟形成
Oxime formation between alpha-keto acids and L-canaline.
作者信息
Cooper A J
出版信息
Arch Biochem Biophys. 1984 Sep;233(2):603-10. doi: 10.1016/0003-9861(84)90485-5.
PMID:6486804
Abstract
Canaline reacts rapidly with glyoxylate, but more slowly with other alpha-keto acids, to form stable oximes. Oxidation of L-canaline with L-amino acid oxidase yields the cyclic, internal oxime, isoxazoline-3-carboxylate. L-Canaline-alpha-keto acid oximes are also substrates of L-amino acid oxidase, yielding isoxazoline-3-carboxylate, alpha-keto acid, and ammonia.
摘要
犬尿氨酸与乙醛酸反应迅速，但与其他α-酮酸反应较慢，形成稳定的肟。L-犬尿氨酸经L-氨基酸氧化酶氧化生成环状内肟异恶唑啉-3-羧酸盐。L-犬尿氨酸-α-酮酸肟也是L-氨基酸氧化酶的底物，生成异恶唑啉-3-羧酸盐、α-酮酸和氨。
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