Cooper A J
Arch Biochem Biophys. 1984 Sep;233(2):603-10. doi: 10.1016/0003-9861(84)90485-5.
Canaline reacts rapidly with glyoxylate, but more slowly with other alpha-keto acids, to form stable oximes. Oxidation of L-canaline with L-amino acid oxidase yields the cyclic, internal oxime, isoxazoline-3-carboxylate. L-Canaline-alpha-keto acid oximes are also substrates of L-amino acid oxidase, yielding isoxazoline-3-carboxylate, alpha-keto acid, and ammonia.
犬尿氨酸与乙醛酸反应迅速，但与其他α-酮酸反应较慢，形成稳定的肟。L-犬尿氨酸经L-氨基酸氧化酶氧化生成环状内肟异恶唑啉-3-羧酸盐。L-犬尿氨酸-α-酮酸肟也是L-氨基酸氧化酶的底物，生成异恶唑啉-3-羧酸盐、α-酮酸和氨。
