先天性多发性关节挛缩症合并母亲患多发性硬化症。

Arthrogryposis multiplex congenita occurring with maternal multiple sclerosis.

作者信息

Livingstone I R, Sack G H

出版信息

Arch Neurol. 1984 Nov;41(11):1216-7. doi: 10.1001/archneur.1984.04050220118031.

DOI:10.1001/archneur.1984.04050220118031

Abstract

All children of a mother with multiple sclerosis (MS) had increasing grades of congenital joint contractures without demonstrable neuromuscular disease. Two had talipes equinovarus, one had congenital hip subluxation, and the youngest had arthrogryposis multiplex congenita. Maternal MS may be causally related to the development of congenital joint contractures.

摘要

患有多发性硬化症（MS）的母亲所生的所有孩子都有先天性关节挛缩程度加重的情况，但未发现明显的神经肌肉疾病。两个孩子患有马蹄内翻足，一个孩子患有先天性髋关节半脱位，最小的孩子患有先天性多发性关节挛缩症。母亲患多发性硬化症可能与先天性关节挛缩的发生有因果关系。