Rampen F H, Kint A, Hunter J A, Hulsebosch H J
Br J Dermatol. 1984 Oct;111(4):431-6. doi: 10.1111/j.1365-2133.1984.tb06605.x.
A questionnaire was sent to all consultant dermatologists in The Netherlands, Belgium and Scotland regarding their management of suspected melanomas. The 343 evaluable responses showed that 29.7% of the dermatologists regularly prefer to 'wait and see' or carry out incisional biopsies in the early management of suspected melanoma, especially if the risk is thought low. The main arguments advanced by the proponents of incision were doubts about whether incisional biopsy provokes metastatic spread, and the belief that a pathologist can make reliable diagnosis on a partial specimen of the tumour. These arguments are questioned and excision biopsy, provided it is feasible without being disfiguring, is strongly recommended in the initial treatment of a suspected melanoma.
一份调查问卷被发送给了荷兰、比利时和苏格兰的所有皮肤科顾问医生，询问他们对疑似黑色素瘤的处理方式。343份可评估的回复显示，29.7%的皮肤科医生在疑似黑色素瘤的早期处理中通常更倾向于“观察等待”或进行切开活检，尤其是在认为风险较低时。支持切开活检的人提出的主要理由是，怀疑切开活检是否会引发转移扩散，以及认为病理学家能够根据肿瘤的部分标本做出可靠诊断。这些理由受到了质疑，并且强烈建议在疑似黑色素瘤的初始治疗中进行切除活检，前提是可行且不会造成毁容。
