An X-ray diffraction and electron microscopy study of the extraction of erythrocyte membranes with the bile salt, cholate.
作者信息
Finean J B, Gunn T K, Hutchinson A, Mills D
出版信息
Biochim Biophys Acta. 1984 Oct 17;777(1):140-6. doi: 10.1016/0005-2736(84)90506-6.
PMID:6487616
Abstract
Studies by X-ray diffraction and electron microscopy of slowly frozen samples of control and cholate-extracted preparations of erythrocyte membranes have demonstrated changes in structural parameters which can readily be related to the extraction of cytoskeletal proteins. In the frozen state, these components appear to be condensed to about 10% of the total membrane thickness. The observations illustrate some of the advantages and limitations in the use of slowly frozen membrane preparations in studies of membrane structure.
摘要
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