Feenstra B W, Hofman F, Van Leeuwen J J
Biol Cybern. 1984;50(6):409-18. doi: 10.1007/BF00335198.
A compartmental model of a terrapin motoneuron has been set up to compute membrane potential variations associated with synaptic input at different locations or with antidromic invasion. Membrane potential distributions obtained in that way were used to compute field potentials by means of a volume conduction formalism. The model was used to simulate field potentials measured in the spinal cord in response to stimulation of a muscle nerve with the intention to discriminate between different activation hypothesis for the generation of the spinal cord potential. Extracellular potentials calculated with an excitatory input distributed over the whole dorsal dendritic tree were found to give better reconstruction when compared with excitation restricted to the distal part of the dorsal dendrites, or with somatic inhibition.
已经建立了一个龟运动神经元的房室模型，以计算与不同位置的突触输入或逆行入侵相关的膜电位变化。通过这种方式获得的膜电位分布被用于借助体积传导形式来计算场电位。该模型被用于模拟脊髓中响应肌肉神经刺激而测量的场电位，目的是区分脊髓电位产生的不同激活假设。与局限于背侧树突远端的兴奋或体细胞抑制相比，发现当兴奋性输入分布在整个背侧树突树上时计算出的细胞外电位能给出更好的重建结果。
