Gasteva S V, Raĭze T E, Sharagina L M
Biull Eksp Biol Med. 1984 Sep;98(9):290-2.
The rate of phospholipid turnover in brain subcellular fractions differ from that in the liver tissue. Hypoxia of medium severity (pressure chamber 240 mm Hg) influences neither the content nor the turnover rate of phospholipids in liver subcellular fractions. Meanwhile in brain subcellular fractions, it results in a decreased phospholipid turnover rate. Severe hypoxia (less than 200 mm Hg) leads only to the suppression of the phospholipid turnover rate in the liver, whereas in the brain, it results in the decline of the phospholipid turnover rate as well as in the reduction of phospholipid content. Thus, the well-known concept of the higher brain sensitivity to oxygen deficiency as compared to the liver is exemplified by phospholipid turnover in subcellular fractions.
脑亚细胞组分中磷脂周转速率与肝组织中的不同。中度缺氧（压力舱240毫米汞柱）对肝亚细胞组分中磷脂的含量和周转速率均无影响。与此同时，在脑亚细胞组分中，它会导致磷脂周转速率降低。严重缺氧（低于200毫米汞柱）仅会抑制肝脏中磷脂的周转速率，而在脑中，它会导致磷脂周转速率下降以及磷脂含量减少。因此，亚细胞组分中的磷脂周转说明了脑对缺氧的敏感性高于肝脏这一众所周知的概念。
