[Protein turnover of subcellular rat liver fractions in a varying protein supply of the body].

Experiments on rats were made to study turnover and the content of total proteins of rat liver subcellular fractions under isocaloric diets with different amounts of protein. As a result of receiving low-protein diets (9 and particularly 4.5% as regards protein), the half-life of 14 C-lysine decreases apart from a certain reduction in the protein content in all the fractions. Upon unchanged protein content in respect of the control (18% protein), high-protein diet also leads to the half-life diminution. An increase in protein turnover by 4.5% as regards protein in the diet correlates with overall and specific activities of cytochromooxidase in the inner membranes of mitochondria.