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[出生后早期暴露于寒冷环境的大鼠的体温调节特征]

[Thermoregulation characteristics of rats exposed to cold in the early postnatal period].

作者信息

Seliatitskaia V G, Moshkin M P, Romashov N A, Arshinova T V, Salganik R I

出版信息

Biull Eksp Biol Med. 1984 Sep;98(9):356-9.

PMID:6487796
Abstract

Cold adaptation of adult rats (at 4-5 degrees C for 7 weeks) increased their ability to respond to noradrenaline by the rise of body temperature and heat radiation, led to an almost 2-fold increase in the relative brown fat mass (BFM). Adult rats which experienced "cold imprinting" (from the first to the seventh day after birth, 15 min at 4-5 degrees C) showed a far less increment of the BFM on cold adaptation, no additional rise of body temperature and heat radiation in response to noradrenaline. In cold-imprinted rats, the relative surface of the tail and the body surface heat radiation transfer conefficient were found to be reduced. This attests to stable adaptive changes in physical thermoregulation, directed toward increase in animals' heat insulation.

摘要

成年大鼠的冷适应(在4-5摄氏度下持续7周)通过体温升高和热辐射增强了它们对去甲肾上腺素的反应能力,导致相对棕色脂肪量(BFM)几乎增加了两倍。经历“冷印记”(出生后第一天至第七天,在4-5摄氏度下15分钟)的成年大鼠在冷适应时BFM的增加要少得多,对去甲肾上腺素没有额外的体温升高和热辐射增加。在冷印记大鼠中,发现尾巴的相对表面积和体表热辐射传递系数降低。这证明了物理体温调节方面稳定的适应性变化,旨在增加动物的隔热能力。

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