Yacoub M H, De Gasperis C
G Ital Cardiol. 1978;8(4):406-10.
From 1969 to 1976 at Harefield Hospital 260 patients underwent conservative mitral valve surgery. The different techniques used are described. Of the 223 patients followed up (1 to 8 years, mean follow up 48 months) 73% are asymptomatic, 20% are improved and 7% are the same or worse. A conservative operation is possible in approximately 85% of the cases and according to our results this should be the operation of choice in mitral valve surgery.
1969年至1976年期间，260例患者在哈雷菲尔德医院接受了二尖瓣保守手术。文中描述了所采用的不同技术。在接受随访的223例患者中（随访时间为1至8年，平均随访48个月），73%无症状，20%病情改善，7%病情维持原状或恶化。约85%的病例可以进行保守手术，根据我们的结果，这应该是二尖瓣手术的首选术式。
