Acker H, Pietruschka F
Brain Res. 1984 Oct 8;311(1):148-51. doi: 10.1016/0006-8993(84)91408-2.
Type I cells of embryonic rabbit carotid bodies were cultured under normoxic (21% O2, 10% CO2, 69% N2) and hypoxic (5% O2, 10% CO2, 85% N2) conditions for two days. The mean membrane potential in the hypoxic cultivated type I cells (-27 mV) was significantly higher than in normoxic cultivated cells (-10 mV). The mean input resistance also had the tendency to increase under hypoxic conditions, from 19 m omega to 48 M omega. Results suggest that variations in membrane potential of type I cells due to oxygen pressure changes are an expression of the important role of these cells in oxygen sensing by the carotid body.
将胚胎兔颈动脉体的I型细胞在常氧（21% O₂、10% CO₂、69% N₂）和低氧（5% O₂、10% CO₂、85% N₂）条件下培养两天。低氧培养的I型细胞的平均膜电位（-27 mV）显著高于常氧培养的细胞（-10 mV）。平均输入电阻在低氧条件下也有增加的趋势，从19 mΩ增加到48 MΩ。结果表明，I型细胞的膜电位因氧分压变化而产生的改变是这些细胞在颈动脉体氧感知中起重要作用的一种表现。
