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[马达加斯加的虫媒病毒与狐猴:用黄热病病毒减毒株对褐美狐猴进行实验性感染]

[Arboviruses and lemurs in Madagascar: experimental infection of Lemur fulvus with attenuated strains of yellow fever virus].

作者信息

Rodhain F

出版信息

Bull Soc Pathol Exot Filiales. 1984 May-Jun;77(3):255-62.

PMID:6488418
Abstract

Experimental infections of the malagasy Lemur fulvus have been carried out with two yellow fever virus attenuated strains (17D and FNV vaccine strains). A viremia is detected, with FNV virus only, between the 1rst and 11th day after inoculation. Haemagglutination inhibiting, complement fixing and neutralizing antibodies appear around the 10th day; the study of their dynamics shows their persistence through less than 6 months. These preliminary experiments are the first of a series of infections of malagasy lemurs by several Flaviviruses. The results might allow to evaluate the epidemiological role played by these prosimian primates in the arbovirus cycles in Madagascar.

摘要

已使用两种黄热病病毒减毒株(17D和FNV疫苗株)对马达加斯加褐狐猴进行了实验性感染。接种后第1天至第11天仅检测到FNV病毒血症。血凝抑制、补体结合和中和抗体在第10天左右出现;对其动态变化的研究表明,它们的持续时间不到6个月。这些初步实验是马达加斯加狐猴感染几种黄病毒系列实验中的首例。这些结果可能有助于评估这些原猴灵长类动物在马达加斯加虫媒病毒传播循环中所起的流行病学作用。

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